National Institute of Health Research

HTA commissioning briefs of continuing interest

The following topics have been previously advertised, but we were unable to commission research projects at the time. As they remain of interest, applications have re-opened.

As time has passed since the topics were originally advertised, it is important that applicants justify the importance of the research, and set it in the context of the current evidence landscape in the area. 

These briefs are challenging, so researchers may wish to suggest a different approach than that outlined in the commissioning brief; if so then please fully justify your alternative approach.  

Applications received by the closing date will be reviewed by the funding board. If no applications are received, the brief will be re-advertised.

Primary research applications follow a two-stage process; an Expression of Interest (EoI) on the new HTA EoI application form, followed by a more detailed full application. Evidence synthesis topics follow a one-stage application process, using the full application form.

Please note that commissioning briefs take priority over applications to researcher led funding calls. If an Expression of Interest (EoI) is submitted to the research-led programme on a similar topic to a commissioning brief or any proposed research areas for HTA commissioned calls, it will not be considered and either:

  • once the commissioning brief is advertised, the applicant can tailor their application to the commissioning brief and submit it in response to this


  • if a decision is made not to advertise a commissioning brief, applicants can apply through the researcher-led workstream in the usual way. 

There are currently no funding opportunities available.


Supporting information

*Please note: This document is to be used as a guide and to assist with completion of the on-line application form only; for example, to see how many characters are accepted in each section, and how the printed complete form is laid out. Please do not try to use this as an application form; you must apply using the online form available through the links available when calls are open. You should also refer to the application form guidance notes, which can be found next to the ‘Apply Now’ button.

All primary research projects are expected to establish a programme appointed Trial Steering Committee and it is important that you read the TSC/SSC Guidance (pdf, 203.37 KB) before completing your application. Costs incurred by this committee should be included in the budget as appropriate. 

You may find the following presentations helpful when preparing your application: 

Contact us

If you have any feedback on this process, please email For help and support using the form, please contact us on 023 8059 5544.