National Institute of Health Research

HTA commissioned funding opportunities

The HTA commissioned workstream commissions research proposals that address specific topics or themes, as identified by the HTA boards and panels. There are three rounds a year (opening March, July and October) containing up to 20 separate call topics.

The following commissioning briefs are now available. This page contains all the documents and information you need to complete your proposal form. Please read the instructions carefully.

View a list of proposed topics for future HTA commissioned research.

View commissioning briefs of continuing interest

 

Evidence Synthesis - one stage (full proposal)

Deadline for applications - 1pm, 15 September 2016

TopicDeadlineCommissioning briefGuidance notesApply
16/103 - Imaging for detection of osteomyelitis15 September 2016, by 1pmAccess commissioning brief (pdf, 173.05 KB) Link open in a new windowAccess guidance notes (pdf, 586.01 KB) Link open in a new windowApply
16/104 - Intensive behavioural interventions based on applied behaviour analysis for young children with autism15 September 2016, by 1pm
Access commissioning brief (pdf, 183.4 KB) Link open in a new window
Access guidance notes (pdf, 586.01 KB) Link open in a new window
Apply

 

Primary Research - two stages (HTA expressions of interest to full proposal)

Deadline for applications - 1pm, 15 September 2016

TopicDeadlineCommissioning briefGuidance notesApply
16/18 - Topiramate for posttraumatic stress disorder
15 September 2016, by 1pm
Access commissioning brief  (pdf, 138.88 KB)Link open in a new window 
Access guidance notes (pdf, 269.17 KB)Link open in a new window 
Apply
16/24 - Biological response modifier drugs for rare autoimmune diseases
15 September 2016, by 1pm
Access commissioning brief (pdf, 139.11 KB) Link open in a new window
Access guidance notes (pdf, 269.17 KB)Link open in a new window 
Apply
16/25 - Poorly controlled diabetes and outcomes of elective surgery
15 September 2016, by 1pm
Access commissioning brief (pdf, 187.09 KB) Link open in a new window
Access guidance notes (pdf, 269.17 KB)Link open in a new window 
Apply
16/73 - Treatment for 3 and 4 part proximal humeral fractures
15 September 2016, by 1pmAccess commissioning brief (pdf, 139.27 KB) Link open in a new windowAccess guidance notes (pdf, 269.17 KB)Link open in a new window 
Apply
16/74 - Optimal treatment strategies for fistulising perianal Crohn’s disease
15 September 2016, by 1pm
Access commissioning brief (pdf, 283.05 KB) Link open in a new window
Access guidance notes (pdf, 269.17 KB)Link open in a new window 
Apply
16/75 - Zoledronic acid to reduce fractures in patients with alcoholic liver disease
15 September 2016, by 1pm
Access commissioning brief (pdf, 140.58 KB) Link open in a new window
Access guidance notes (pdf, 269.17 KB)Link open in a new window 
Apply
16/76 - Management of an impacted fetal head during emergency caesarean section
15 September 2016, by 1pm
Access commissioning brief (pdf, 185 KB) Link open in a new window
Access guidance notes (pdf, 269.17 KB)Link open in a new window 
Apply
16/77 - Induction of labour at 39 weeks for predicted macrosomia
15 September 2016, by 1pm
Access commissioning brief (pdf, 185.46 KB) Link open in a new window
Access guidance notes (pdf, 269.17 KB)Link open in a new window 
Apply
16/79 - Optimising nutrition during therapeutic hypothermia
15 September 2016, by 1pm
Access commissioning brief (pdf, 180.81 KB) Link open in a new window
Access guidance notes (pdf, 269.17 KB)Link open in a new window 
Apply
16/80 - Melatonin for preoperative distress in children
15 September 2016, by 1pm
Access commissioning brief (pdf, 144 KB) Link open in a new window
Access guidance notes (pdf, 269.17 KB)Link open in a new window 
Apply
16/81 - Intervention to improve the psychological health of people with motor neurone disease
15 September 2016, by 1pmAccess commissioning brief (pdf, 187.83 KB) Link open in a new windowAccess guidance notes (pdf, 269.17 KB)Link open in a new window 
Apply
16/82 - Self-management of vaginal pessaries for pelvic organ prolapse
15 September 2016, by 1pm
Access commissioning brief (pdf, 184.03 KB) Link open in a new windowAccess guidance notes (pdf, 269.17 KB)Link open in a new window 
Apply
16/83 - Faecal immunochemical testing in primary care or rapid access clinics
15 September 2016, by 1pm
Access commissioning brief (pdf, 138.78 KB) Link open in a new windowAccess guidance notes (pdf, 269.17 KB)Link open in a new window 
Apply
16/84 - Simplified sleep restriction in primary care
15 September 2016, by 1pm
Access commissioning brief (pdf, 139.49 KB) Link open in a new window
Access guidance notes (pdf, 269.17 KB)Link open in a new window 
Apply
16/85 - Antibiotics for acute otitis media with discharge
15 September 2016, by 1pm
Access commissioning brief (pdf, 140.41 KB) Link open in a new window
Access guidance notes (pdf, 269.17 KB)Link open in a new window 
Apply
16/86 - Non-pharmacological interventions to treat visuoperceptual disorders following stroke
15 September 2016, by 1pm
Access commissioning brief (pdf, 184.37 KB) Link open in a new window
Access guidance notes (pdf, 269.17 KB)Link open in a new window 
Apply
16/88 - Improving adherence to tuberculosis treatment15 September 2016, by 1pm
Access commissioning brief (pdf, 139.99 KB) Link open in a new window
Access guidance notes (pdf, 269.17 KB)Link open in a new window 
Apply
16/90 - Non-pharmacological and non-surgical interventions for men with lower urinary tract symptoms
15 September 2016, by 1pm
Access commissioning brief (pdf, 181.08 KB) Link open in a new window
Access guidance notes (pdf, 269.17 KB)Link open in a new window 
Apply
16/113 - Regular home visits to older patients at risk of unscheduled hospitalisation
15 September 2016, by 1pm
Access commissioning brief (pdf, 111.07 KB) Link open in a new window
Access guidance notes (pdf, 269.17 KB)Link open in a new window 
Apply

Primary Research topics inviting collaborative applications from UK and Australian researchers - two stages (HTA expressions of interest to full proposal)

Deadline 1pm, 15 September 2016

These topics have been identified as an opportunity for collaboration between Australia’s National Health and Medical Research Council (NHMRC) and the UK National Institute for Health Research (NIHR) HTA Programme and we welcome joint applications from Australian and UK researchers in addition to standalone applications from UK based researchers.

TopicDeadlineCommissioning BriefGuidance notesApply
16/17 - Prophylactic antibiotics to prevent recurrent lower respiratory tract infections in children with neurological impairment

15 September 2016, by 1pm

Access commissioning brief (pdf, 248.67 KB) Link open in a new windowAccess guidance notes (pdf, 269.17 KB)  Link open in a new windowApply

16/22 - Smoking cessation interventions in children of school age

15 September 2016, by 1pm

Access commissioning brief (pdf, 247.48 KB) Link open in a new window
Access guidance notes (pdf, 269.17 KB) Link open in a new window
Apply


Primary Research - two stages (HTA expressions of interest to full proposal)

Deadline for applications - 1pm, 7 February 2017

TopicDeadlineCommissioning briefGuidance notesApply
16/78 - Timing of defibulation surgery for women who have undergone female genital mutilation
7 February 2017, by 1pm
Access commissioning brief (pdf, 182.18 KB) Link open in a new window
Access guidance notes (pdf, 269.17 KB)Link open in a new window 
Apply
16/89 - Interventions for small bowel Crohn's disease
7 February 2017, by 1pmAccess commissioning brief (pdf, 187.02 KB) Link open in a new windowAccess guidance notes (pdf, 269.17 KB)Link open in a new window 
Apply
16/91 - Take home naloxone for opiate overdose
7 February 2017, by 1pm
Access commissioning brief (pdf, 151.78 KB) Link open in a new window
Access guidance notes (pdf, 269.17 KB)Link open in a new window 
Apply
16/92 - The role of prophylactic antibiotics for botulinum toxin A injections for overactive bladder
7 February 2017, by 1pm
Access commissioning brief(pdf, 137.98 KB) Link open in a new window
Access guidance notes (pdf, 269.17 KB)Link open in a new window 
Apply
16/93 - Alpha-2 agonists for sedation in critical care
7 February 2017, by 1pm
Access commissioning brief (pdf, 181.36 KB) Link open in a new window
Access guidance notes (pdf, 269.17 KB)Link open in a new window 
Apply
16/94 - Gastric residual volume measurement in mechanically ventilated infants and children
7 February 2017, by 1pm
Access commissioning brief (pdf, 186.38 KB) Link open in a new window
Access guidance notes (pdf, 269.17 KB)Link open in a new window 
Apply
16/95 - Management of sexual dysfunction associated with antipsychotic drug therapy
7 February 2017, by 1pm
Access commissioning brief (pdf, 197.64 KB) Link open in a new window
Access guidance notes (pdf, 269.17 KB)Link open in a new window 
Apply
16/96 - Standardised diagnostic assessment tool as an adjunct to clinical practice in child and adolescent mental health services
7 February 2017, by 1pm
Access commissioning brief (pdf, 185.19 KB) Link open in a new window
Access guidance notes (pdf, 269.17 KB)Link open in a new window 
Apply
16/97 - Antipsychotics for anorexia nervosa
7 February 2017, by 1pm
Access commissioning brief (pdf, 143.87 KB) Link open in a new window
Access guidance notes (pdf, 269.17 KB)Link open in a new window 
Apply
16/98 - Down-titration of alendronate dosage
7 February 2017, by 1pm
Access commissioning brief (pdf, 183.75 KB) Link open in a new windowAccess guidance notes (pdf, 269.17 KB)Link open in a new window 
Apply
16/99 - Primary prevention of variceal bleeding in patients with liver cirrhosis
7 February 2017, by 1pm
Access commissioning brief (pdf, 187.29 KB) Link open in a new windowAccess guidance notes (pdf, 269.17 KB)Link open in a new window 
Apply
16/100 - Stem cell transplant in adults with severe sickle cell disease
7 February 2017, by 1pm
Access commissioning brief (pdf, 184.94 KB) Link open in a new windowAccess guidance notes (pdf, 269.17 KB)Link open in a new window 
Apply
16/101 - De-escalation techniques and the use of restrictive interventions in adult mental health units
7 February 2017, by 1pm
Access commissioning brief (pdf, 195.82 KB) Link open in a new window
Access guidance notes (pdf, 269.17 KB)Link open in a new window 
Apply
16/102 - Understanding the impact of noisy breathing on carer distress and the use of antimuscarinic drugs at the end of life
7 February 2017, by 1pm
Access commissioning brief (pdf, 294.5 KB) Link open in a new window
Access guidance notes (pdf, 269.17 KB)Link open in a new window 
Apply
16/109 - Reduced fluid resuscitation regimen for burn injuries7 February 2017, by 1pm
Access commissioning brief (pdf, 140.25 KB) Link open in a new windowAccess guidance notes (pdf, 269.17 KB)Link open in a new window
Apply

Timelines - initial application to project start

Applications received by 15 September 2016 will be considered at the HTA Funding Board in November 2016. Following the Board meeting, successful first stage applicants will be invited to submit a full proposal. Applicants will have eight weeks to complete and submit a full application form, which will then be considered at the following HTA Funding Board in March 2017.

Applications received by 7 February 2017 will be considered at the HTA Funding Board in March 2017. Following the Board meeting, successful first stage applicants will be invited to submit a full proposal. Applicants will have eight weeks to complete and submit a full application form, which will then be considered at the following HTA Funding Board in July 2017.


New HTA Expressions of Interest application form 

The HTA Programme is pleased to be launching a pilot for a new Expression of Interest (EoI) application form, which is designed to replace the outline proposal form.  EoIs will proceed to a funding board, with any short-listed applications invited to proceed directly to a full proposal. 

We hosted a webinar on 13 November 2014 presented by Dr Peter Davidson and Dr Martin Ashton-Key, introducing the new Expression of Interest form. You may find this helpful when preparing for your application. Watch the webinar Link open in a new window

Contact us

If you have any feedback on this new form, please email htacmsng@soton.ac.uk. For help and support using the form, please contact us on 023 8059 5510.  

 

Supporting information

*Please note: This document is to be used as a guide and to assist with completion of the on-line application form only; for example, to see how many characters are accepted in each section, and how the printed complete form is laid out. Please do not try to use this as an application form; you must apply using the online form available through the links available when calls are open. You should also refer to the application form guidance notes, which can be found next to the ‘Apply Now’ button.

All primary research projects are expected to establish a programme appointed Trial Steering Committee and it is important that you read the TSC/SSC Guidance (pdf, 203.37 KB) before completing your application. Costs incurred by this committee should be included in the budget as appropriate. 

You may find the following presentations helpful when preparing your application: 

Queries and problems

Our FAQs section provides advice and guidance based on previous queries we have received. You may find this helpful in preparing your proposal.

If you have a query, please contact: HTA Commissioning Team, Tel: +44 (0)23 8059 5510  or +44 (0)23 8059  5621 (24 hour answerphone) Fax No: 023 8059 5639, Email: htacmsng@southampton.ac.uk