National Institute of Health Research

HTA commissioned funding opportunities

The HTA commissioned workstream commissions research proposals that address specific topics or themes, as identified by the HTA boards and panels. There are three rounds a year (opening March, July and October) containing up to 20 separate call topics.

The following commissioning briefs are now available. This page contains all the supporting documents and information you need to complete your proposal form. Please read the instructions carefully.

Please note that commissioning briefs take priority over applications to researcher led funding calls. If an Expression of Interest (EoI) is submitted to the research-led programme on a similar topic to a commissioning brief or any proposed research areas for HTA commissioned calls, it will not be considered and either:

  • once the commissioning brief is advertised, the applicant can tailor their application to the commissioning brief and submit it in response to this

    or

  • if a decision is made not to advertise a commissioning brief, applicants can apply through the researcher-led workstream in the usual way. 

View a list of proposed topics for future HTA commissioned research.

View commissioning briefs of continuing interest

Primary Research - two stages (HTA expressions of interest to full proposal)

Deadline for applications - 1pm, 7 February 2017

TopicDeadlineCommissioning briefGuidance notesApply
16/78 - Timing of defibulation surgery for women who have undergone female genital mutilation
7 February 2017, by 1pm
Access commissioning brief (pdf, 248.44 KB) Link open in a new window
Access guidance notes (pdf, 445.45 KB)Link open in a new window 
Apply
16/89 - Interventions for small bowel Crohn's disease
7 February 2017, by 1pmAccess commissioning brief (pdf, 187.02 KB) Link open in a new windowAccess guidance notes (pdf, 445.45 KB)Link open in a new window 
Apply
16/91 - Take home naloxone for opiate overdose
7 February 2017, by 1pm
Access commissioning brief (pdf, 151.78 KB) Link open in a new window
Access guidance notes (pdf, 445.45 KB)Link open in a new window 
Apply
16/92 - The role of prophylactic antibiotics for botulinum toxin A injections for overactive bladder
7 February 2017, by 1pm
Access commissioning brief(pdf, 137.98 KB) Link open in a new window
Access guidance notes (pdf, 445.45 KB)Link open in a new window 
Apply
16/93 - Alpha-2 agonists for sedation in critical care
7 February 2017, by 1pm
Access commissioning brief (pdf, 181.36 KB) Link open in a new window
Access guidance notes (pdf, 445.45 KB)Link open in a new window 
Apply
16/94 - Gastric residual volume measurement in mechanically ventilated infants and children
7 February 2017, by 1pm
Access commissioning brief (pdf, 186.38 KB) Link open in a new window
Access guidance notes (pdf, 445.45 KB)Link open in a new window 
Apply
16/95 - Management of sexual dysfunction associated with antipsychotic drug therapy
7 February 2017, by 1pm
Access commissioning brief (pdf, 197.64 KB) Link open in a new window
Access guidance notes (pdf, 445.45 KB)Link open in a new window 
Apply
16/96 - Standardised diagnostic assessment tool as an adjunct to clinical practice in child and adolescent mental health services
7 February 2017, by 1pm
Access commissioning brief (pdf, 185.19 KB) Link open in a new window
Access guidance notes (pdf, 445.45 KB)Link open in a new window 
Apply
16/97 - Antipsychotics for anorexia nervosa
7 February 2017, by 1pm
Access commissioning brief (pdf, 143.87 KB) Link open in a new window
Access guidance notes (pdf, 445.45 KB)Link open in a new window 
Apply
16/98 - Down-titration of alendronate dosage
7 February 2017, by 1pm
Access commissioning brief (pdf, 183.75 KB) Link open in a new windowAccess guidance notes (pdf, 445.45 KB)Link open in a new window 
Apply
16/99 - Primary prevention of variceal bleeding in patients with liver cirrhosis
7 February 2017, by 1pm
Access commissioning brief (pdf, 187.29 KB) Link open in a new windowAccess guidance notes (pdf, 445.45 KB)Link open in a new window 
Apply
16/100 - Stem cell transplant in adults with severe sickle cell disease
7 February 2017, by 1pm
Access commissioning brief (pdf, 184.94 KB) Link open in a new windowAccess guidance notes (pdf, 445.45 KB)Link open in a new window 
Apply
16/101 - De-escalation techniques and the use of restrictive interventions in adult mental health units
7 February 2017, by 1pm
Access commissioning brief (pdf, 195.82 KB) Link open in a new window
Access guidance notes (pdf, 445.45 KB)Link open in a new window 
Apply
16/102 - Understanding the impact of noisy breathing on carer distress and the use of antimuscarinic drugs at the end of life
7 February 2017, by 1pm
Access commissioning brief (pdf, 294.5 KB) Link open in a new window
Access guidance notes (pdf, 445.45 KB)Link open in a new window 
Apply
16/109 - Reduced fluid resuscitation regimen for burn injuries7 February 2017, by 1pm
Access commissioning brief (pdf, 140.25 KB) Link open in a new windowAccess guidance notes (pdf, 445.45 KB)Link open in a new window
Apply

Primary Research - two stages (HTA expressions of interest to full proposal)

Deadline for applications - 1pm, 9 February 2017

TopicDeadlineCommissioning briefGuidance notesApply
16/140 - Preoperative Inspiratory Muscle Training
9 February 2017, by 1pm
Access commissioning brief (pdf, 337.32 KB) Link open in a new window
Access guidance notes (pdf, 445.45 KB)Link open in a new window 
Apply
16/141 - Proton pump inhibitor therapy for refractory gastro-oesophageal reflux symptoms
9 February 2017, by 1pm
Access commissioning brief (pdf, 293.06 KB) Link open in a new window
Access guidance notes (pdf, 445.45 KB)Link open in a new window 
Apply
16/142 - The role of bile duct imaging in gallbladder surgery
9 February 2017, by 1pm
Access commissioning brief (pdf, 338.05 KB) Link open in a new window
Access guidance notes (pdf, 445.45 KB)Link open in a new window 
Apply
16/143 - Frenotomy for babies with tongue-tie
9 February 2017, by 1pm
Access commissioning brief (pdf, 293.24 KB) Link open in a new window
Access guidance notes (pdf, 445.45 KB)Link open in a new window 
Apply
16/144 - Responsive vs scheduled feeding for preterm infants
9 February 2017, by 1pm
Access commissioning brief (pdf, 338.99 KB) Link open in a new window
Access guidance notes (pdf, 445.45 KB)Link open in a new window 
Apply
16/145 - Antidepressants for depression in people with Parkinson’s disease
9 February 2017, by 1pm
Access commissioning brief (pdf, 449.49 KB) Link open in a new window
Access guidance notes (pdf, 445.45 KB)Link open in a new window 
 Apply

Evidence synthesis - one stage (straight to full proposal)

Deadline for applications - 1pm, 9 February 2017

TopicDeadlineCommissioning briefGuidance notesApply
16/146 - Oral splints for orofacial symptoms9 February 2017, by 1pm
Access commissioning brief (pdf, 174.72 KB) Link open in a new window
Access guidance notes (pdf, 594.94 KB) Link open in a new window 
Apply

Primary Research - two stages (HTA expressions of interest to full proposal)

Deadline for applications - 1pm, 6 April 2017

TopicDeadlineCommissioning briefGuidance notesApply
16/147 - Pharmacological management of post-traumatic seizures
6 April 2017, by 1pm
Access commissioning brief (pdf, 336.32 KB) Link open in a new window
Access guidance notes (pdf, 445.45 KB)Link open in a new window 
Apply
16/148 - Treatments for women with recurrent stress urinary incontinence after failed primary surgery
6 April 2017, by 1pm
Access commissioning brief (pdf, 293.14 KB) Link open in a new window
Access guidance notes (pdf, 445.45 KB)Link open in a new window 
Apply
16/149 - Delivering babies in or out of water
6 April 2017, by 1pm
Access commissioning brief (pdf, 293.38 KB) Link open in a new window
Access guidance notes (pdf, 445.45 KB)Link open in a new window 
Apply
16/150 - Long term impact of pre-incision antibiotics on babies born by caesarean section
6 April 2017, by 1pm
Access commissioning brief (pdf, 292.72 KB) Link open in a new window
Access guidance notes (pdf, 445.45 KB)Link open in a new window 
Apply
16/151 - Rescue cerclage
6 April 2017, by 1pm
Access commissioning brief (pdf, 338.47 KB) Link open in a new window
Access guidance notes (pdf, 445.45 KB)Link open in a new window 
Apply
16/152 - Selective gut decontamination in critically ill children
6 April 2017, by 1pm
Access commissioning brief (pdf, 338.26 KB) Link open in a new window
Access guidance notes (pdf, 445.45 KB)Link open in a new window 
Apply
16/153 - Harm reduction intervention for severe drug and/or alcohol dependence among people who are homeless
6 April 2017, by 1pm
Access commissioning brief (pdf, 295.46 KB) Link open in a new window
Access guidance notes (pdf, 445.45 KB)Link open in a new window 
Apply
16/154 - Pramipexole for treatment resistant bipolar depression
6 April 2017, by 1pm
Access commissioning brief (pdf, 392.91 KB) Link open in a new window
Access guidance notes (pdf, 445.45 KB)Link open in a new window 
Apply
16/155 - Problem solving therapy for depression in older adults with dementia
6 April 2017, by 1pm
Access commissioning brief (pdf, 301.67 KB) Link open in a new window
Access guidance notes (pdf, 445.45 KB)Link open in a new window 
Apply
16/156 - Improving communication for adults with profound and multiple learning disabilities
6 April 2017, by 1pm
Access commissioning brief (pdf, 343.18 KB) Link open in a new window
Access guidance notes (pdf, 445.45 KB)Link open in a new window 
Apply
16/157 - Clozapine in the treatment of borderline personality disorder
6 April 2017, by 1pm
Access commissioning brief (pdf, 298.61 KB) Link open in a new window
Access guidance notes (pdf, 445.45 KB)Link open in a new window 
Apply
16/158 - Reducing the risk of anxiety disorders in children of parents seeking help for their own anxiety
6 April 2017, by 1pm
Access commissioning brief (pdf, 298.33 KB) Link open in a new window
Access guidance notes (pdf, 445.45 KB)Link open in a new window 
Apply
16/159 - A risk assessment tool to help identify prisoners at further risk of self-harm
6 April 2017, by 1pm
Access commissioning brief (pdf, 343.36 KB) Link open in a new window
Access guidance notes (pdf, 445.45 KB)Link open in a new window 
Apply
16/160 - Knee braces in the management of knee osteoarthritis
6 April 2017, by 1pm
Access commissioning brief (pdf, 292.67 KB) Link open in a new window
Access guidance notes (pdf, 445.45 KB)Link open in a new window 
Apply
16/161 - Partial removal of dental caries in permanent teeth
6 April 2017, by 1pm
Access commissioning brief (pdf, 292.74 KB) Link open in a new window
Access guidance notes (pdf, 445.45 KB)Link open in a new window
Apply
16/162 - Low-dose antidepressants for the treatment of irritable bowel syndrome6 April 2017, by 1pmAccess commissioning brief (pdf, 292.53 KB) Link open in a new window
Access guidance notes (pdf, 445.45 KB)Link open in a new window
Apply

Evidence synthesis - one stage (straight to full proposal)

Deadline for applications - 1pm, 6 April 2017

TopicDeadlineCommissioning briefGuidance notesApply
16/165 - Modelling the potential for health gain and cost effectiveness of the NHS Health Check Programme6 April 2017, by 1pm
Access commissioning brief (pdf, 177.63 KB) Link open in a new window
Access guidance notes (pdf, 594.94 KB) Link open in a new window 
Apply

 

Primary Research - two stages (HTA expressions of interest to full proposal)

Deadline for applications - 1pm, 1 June 2017

TopicDeadlineCommissioning briefGuidance notesApply
16/163 - Microbiological sampling and treatment for infection complicating diabetic foot ulceration
1 June 2017, by 1pm
Access commissioning brief (pdf, 294.5 KB) Link open in a new window
Access guidance notes (pdf, 445.45 KB)Link open in a new window 
Apply
16/164 - Unscheduled Bleeding in Women Using Long Acting Reversible Contraception
1 June 2017, by 1pm
Access commissioning brief (pdf, 306.23 KB) Link open in a new window
Access guidance notes (pdf, 445.45 KB)Link open in a new window 
Apply


 

Timelines - initial application to project start

Applications received by 7 February 2017 will be considered at the HTA Funding Board in March 2017. Following the Board meeting, successful first stage applicants will be invited to submit a full proposal. Applicants will have eight weeks to complete and submit a full application form, which will then be considered at the following HTA Funding Board in July 2017.


New HTA Expressions of Interest application form 

The HTA Programme is pleased to be launching a pilot for a new Expression of Interest (EoI) application form, which is designed to replace the outline proposal form.  EoIs will proceed to a funding board, with any short-listed applications invited to proceed directly to a full proposal. 

We hosted a webinar on 13 November 2014 presented by Dr Peter Davidson and Dr Martin Ashton-Key, introducing the new Expression of Interest form. You may find this helpful when preparing for your application. Watch the webinar Link open in a new window

Contact us

If you have any feedback on this new form, please email htacmsng@soton.ac.uk. For help and support using the form, please contact us on 023 8059 5510.  

 

Supporting information

*Please note: This document is to be used as a guide and to assist with completion of the on-line application form only; for example, to see how many characters are accepted in each section, and how the printed complete form is laid out. Please do not try to use this as an application form; you must apply using the online form available through the links available when calls are open. You should also refer to the application form guidance notes, which can be found next to the ‘Apply Now’ button.

All primary research projects are expected to establish a programme appointed Trial Steering Committee and it is important that you read the TSC/SSC Guidance (pdf, 203.37 KB) before completing your application. Costs incurred by this committee should be included in the budget as appropriate. 

You may find the following presentations helpful when preparing your application: 

Queries and problems

Our FAQs section provides advice and guidance based on previous queries we have received. You may find this helpful in preparing your proposal.

If you have a query, please contact: HTA Commissioning Team, Tel: +44 (0)23 8059 5510  or +44 (0)23 8059  5621 (24 hour answerphone) Fax No: 023 8059 5639, Email: htacmsng@southampton.ac.uk